SAR study indicates that the most crucial structural feature of phenolic compounds needed to possess good antiradical and also antioxidant activities will be the presence of a 2nd hydroxyl or a good amino group with o- or p-position for their strong electron giving effect in research chemicals plus the formation of a stable quinone-like products upon two hydrogen-atom transport process; otherwise, the presence of several alkoxy (with o or p-position) as well as /or alkyl teams (in to, m or p-position) need to be present to strengthen the resulted phenoxyl significant and reach beneficial activity.
